Ashwagandha appears to be well-tolerated, however side effects may include diarrhea, vomiting, nausea, or abdominal pain. Severe side effects may include liver failure.
Ashwagandha can interact with some medications. It may increase the sedative effects of alcohol, benzodiazepines (e.g., diazepam, clonazepam, etc.), barbiturates (e.g., phenobarbital), other sedatives and anxiety-relieving medications and herbal products, and thyroid supplements.
It can add to the blood-pressure-lowering effects of blood pressure medications. It can also add to the blood sugar lowering effects of medications for diabetes.
Ashwagandha may also decrease the effects of medications that suppress the immune system (e.g., cyclosporine, corticosteroids). Ashwagandha may increase the effects of thyroid hormone medications. If you are taking any of these medications or herbal products, talk to your health care provider before using ashwagandha.
You should avoid ashwagandha if you:
- have hyperthyroidism or are taking thyroid hormone medications
- have an autoimmune medical condition (e.g., multiple sclerosis, rheumatoid arthritis)
- have an allergy to ashwagandha
If insomnia persists for more than 4 weeks after taking ashwagandha, talk to your doctor.
You should not use ashwagandha if you are pregnant or breast-feeding, or if you are taking alcohol or other drugs that cause drowsiness. Consult your health care professional if you have any questions.
Before taking any new medications, including natural health products, speak to your physician, pharmacist, or other health care provider. Tell your health care provider about any natural health products you may be taking.